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WOMEN, PREGNANCY & DIABETES

Hot Flashes and Blood Sugar: What the Connection Actually Is

Flushes don't spike your glucose in the moment — but frequent ones say something about what your body is doing in the background.

6 min read
A woman sitting up awake on her bed in a dimly lit room at night, resting her head on her hands
Photo via cottonbro studio / Pexels (opens in a new tab)

The heat rises through your chest and face, you are damp within seconds, and by the time it passes you are wondering whether you should go and check your sugar. It is a reasonable instinct. Something clearly just happened in your body, and everything else that happens in your body seems to show up in your readings.

So here is the honest shape of it. A hot flush is not a blood sugar event. It will not, on its own, push your glucose up or down in any way your meter reliably shows. But women who get frequent flushes do, as a group, have more insulin resistance and go on to develop type 2 diabetes more often than women who don't. The connection is real. It just runs deeper and slower than the flush itself.

What the research actually found

Most of what is known here comes from one long study — the Study of Women's Health Across the Nation, which followed thousands of American women through midlife with annual questionnaires and fasting blood draws.

The first finding was about insulin. Across 3,075 women followed for eight years, Thurston and colleagues found that hot flashes tracked with insulin resistance (opens in a new tab): women reporting flushes on one to five days had HOMA scores about 2.4% higher than women with none, and women reporting them on six or more days about 5.9% higher. Those are small numbers, and glucose itself barely moved. What made them interesting is that the link held even after accounting for oestrogen and FSH levels — so this is not simply "low oestrogen causes both."

The second finding was about what comes later. In 2024, a SWAN analysis published in JAMA Network Open (opens in a new tab) followed 2,761 women across 13 visits, during which 338 of them — 12.2% — developed type 2 diabetes. Women with frequent vasomotor symptoms had a 45% higher risk of developing diabetes, and women whose symptoms stayed high year after year had about 50% higher risk. That held after adjusting for weight, physical activity and where they were in the transition.

Note: Fifty percent higher than what

Relative risk figures sound larger than they are. Roughly one in eight women in this study developed diabetes over the follow-up. A 50% higher risk moves a woman from that baseline to something closer to one in five or six — meaningful, worth acting on, and still not a prediction about you personally.

Night sweats deserve their own line

Buried in that 2024 analysis is a detail worth pulling out: persistent night sweats carried a stronger association with diabetes (HR 1.86) than persistent daytime hot flashes (HR 1.64). Sleeping through them is not the same as being unaffected by them.

The study cannot tell us why, but there is an obvious candidate. Night sweats fragment sleep, and broken short sleep is one of the better-established ways to make the body less sensitive to insulin. If your flushes are mostly nocturnal, the sweating may matter less than the four separate wakings around it — and that part is treatable.

A flush is not proof, and it is not a verdict

None of this means flushes cause diabetes, and nothing in it says a woman with bad flushes is heading somewhere bad. What it reasonably means is this: if you are in your forties or fifties and having frequent flushes or night sweats, you are in a group where screening is worth doing on schedule rather than when something feels wrong. If you already have diabetes, frequent flushes are a hint that this stretch may be a harder one for your numbers, and worth watching more closely for a while rather than assuming your usual doses still fit.

One thing not to do is treat every flush as a low. Sweating, pounding heart and shakiness describe both a flush and a hypo almost identically, and guessing wrong in either direction costs you something — we covered how to tell them apart in [menopause and blood sugar](/blog/menopause-and-blood-sugar-what-changes-and-why).

What actually reduces the flushes

This is where a lot of money gets spent on things that don't work. The Menopause Society's 2023 review of non-hormonal treatments (opens in a new tab) sorted the options by how well they hold up in trials, and the results are not what most of us have been told.

ApproachWhat the evidence shows
Cognitive behavioural therapy, clinical hypnosisRecommended. Hypnosis in particular has reduced flush frequency substantially in trials.
SSRIs/SNRIs, gabapentin, fezolinetantRecommended prescription non-hormonal options. Availability and cost vary in Pakistan — ask your doctor what is actually stocked.
Menopausal hormone therapyNot covered by that review, but still the most effective treatment for flushes. Having diabetes does not rule it out; it is a discussion to have with your doctor.
Herbal supplements, soy, black cohosh, flaxseedNot recommended. [NCCIH](https://www.nccih.nih.gov/health/menopausal-symptoms-in-depth) reports inconsistent or null results across these, with no supplement clearly shown to help.
Cooling, avoiding triggers, paced breathing, acupunctureNot recommended as treatments — they have not been shown to reduce flushes, though comfort measures are harmless.

That last row needs a note, because it reads harsher than it should. The NHS still suggests (opens in a new tab) light clothing, a cool bedroom, a fan, a cold drink. Those things make a flush more bearable while it is happening. They just don't appear to make flushes less frequent, so if you have been layering fixes like this and feeling like you are failing at it, you aren't — you were given comfort measures and told they were treatment.

The supplement row matters more here than it would elsewhere. Menopause and diabetes together attract an enormous amount of herbal marketing in Pakistan, and something sold for flushes is often sold alongside something sold for sugar. Bring anything you are taking to your doctor before it sits quietly alongside your prescriptions.

The Pakistani picture is quieter than the international one

If flushes are not the symptom dominating your experience of this transition, you are in good company. In a study of 130 naturally menopausal women in villages outside Lahore (opens in a new tab), hot flushes were reported by 36.2% — while lethargy (65.4%), forgetfulness (57.7%) and urinary symptoms (56.2%) were far more commonly named.

That ordering is worth sitting with, because lethargy, poor concentration and frequent urination are also exactly what uncontrolled blood sugar feels like. In a season when everything gets attributed to "the change," the symptoms most Pakistani women actually report are the ones least able to tell you which of the two you are dealing with. A test can. Your description of how you feel cannot.

Let the pattern show itself

For a few weeks, note your flushes and broken nights next to your readings. If nothing lines up, you have ruled something out. If your worst mornings follow your worst nights, you have found something you can actually take to your doctor.

Start logging with Diatic (opens Diatic on Google Play in a new tab)

Frequently asked questions

My flushes got worse after I started insulin. Is the insulin causing them?

There is no established mechanism by which insulin triggers flushes, and the timing is usually coincidence — insulin often gets started in exactly the years the transition intensifies. What can look similar is that better-controlled sugar sometimes makes low readings more noticeable, and hypo symptoms overlap heavily with flush symptoms. Checking during a few episodes will tell you which you are having.

Do hot flushes stop once blood sugar is well controlled?

No. Improving your control is worth doing for many reasons, but flushes are driven by the hormonal transition, not by your glucose level, and they generally follow their own timeline regardless. The relationship in the research runs from symptoms to metabolic risk, not from glucose to symptoms.

If frequent flushes raise diabetes risk, should I be tested more often than every three years?

That is a question for your doctor, but frequent vasomotor symptoms are a fair reason to raise it. The researchers themselves suggested women with persistent symptoms may be a sensible group to target for prevention. If you also have a family history, a past gestational diabetes, PCOS, or a raised waist measurement, that case gets stronger.

Can hot flushes happen to men with diabetes?

Flushing and sweating episodes in men are usually something else — low blood sugar being one of the more common explanations, alongside certain medications and thyroid problems. They are not a male version of menopausal flushes, and are worth investigating rather than dismissing.

Sources

  1. American Diabetes Association (ADA) (opens in a new tab)
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  17. American Diabetes Association, Standards of Care in Diabetes 2026 (Section 2) (opens in a new tab)
  18. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (opens in a new tab)
  19. Journal of Clinical Endocrinology & Metabolism (Thurston et al., SWAN, 2012) (opens in a new tab)
  20. JAMA Network Open (Hedderson et al., SWAN, 2024) (opens in a new tab)
  21. The Menopause Society (2023 Nonhormone Therapy Position Statement) (opens in a new tab)
  22. National Center for Complementary and Integrative Health (NCCIH) (opens in a new tab)
  23. Journal of Ayub Medical College Abbottabad (rural Lahore menopause study) (opens in a new tab)
  24. NHS (opens in a new tab)
  25. Anagnostis et al., European Journal of Endocrinology (2019 systematic review and meta-analysis) (opens in a new tab)
  26. Maturitas / PubMed (2023 systematic review and meta-analysis of long-term cardiometabolic disease after premature or early menopause) (opens in a new tab)
  27. ESHRE / ASRM Evidence-Based Guideline: Premature Ovarian Insufficiency (Human Reproduction Open, 2024) (opens in a new tab)
  28. Dorman et al., Diabetes (Familial Autoimmune and Diabetes Study) (opens in a new tab)
  29. Yarde et al., Human Reproduction (OVADIA study, 2015) (opens in a new tab)
  30. Hysterectomy and Oophorectomy in Reproductive Age: A Cross-Sectional Study from a Tertiary Care Hospital (Dow Medical College, Karachi) (opens in a new tab)

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